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Average number of CFU of S. aureus covered per hydroxyapatite (HA) disc after 24 h of incubation. HA discs were pretreated with the following formulations: biomineral-binding liposomes (BBL) loaded with oxacillin; non-binding liposomes loaded with oxacillin (NBL); free drug (FD, containing same amount of oxacillin as BBL or NBL); empty biomineral-binding liposomes (EBBL); and untreated control (UC). * P< 0.0001 (Student t-test). All data are expressed as means±standard deviations (n=3).
