Table 3.

Associations between the number of unfavorable genotypes and renal cell carcinoma risk

Variable	Case subjects, No. (%)	Control subjects, No. (%)	OR (95% CI)*	P
No. of unfavorable genotypes†
0	108 (26.87)	136 (31.70)	Referent
1–2	117 (29.10)	149 (34.73)	1.14 (0.79 to 1.66)	.49
3–5	177 (44.03)	144 (33.57)	1.72 (1.20 to 2.46)	.003
Ptrend				.002

* Odds ratios (ORs) were estimated by logistic regression adjusted for age, sex, smoking status, body mass index at 3 years before the diagnosis or recruitment, and hypertension. All statistical tests were two-sided. CI = confidence interval.

† No. of unfavorable genotypes: calculated from rs4132509, rs12031994, rs4430311, rs1058304, and rs23459 94.

Grouping is based on tertiles of the number of unfavorable genotypes in control subjects.

Missing single nucleotide polymorphism data resulted in a lower number of case subjects and control subjects.