Table 1. Baseline Patient Characteristics at first treatment initiation.

	All treatments n = 771	IFNβ-1a IM n = 153	IFNβ-1a SC n = 220	IFNβ-1b n = 270	GA n = 117	NAT n = 11	p-value Between treatment groups
Female n (%)	592 (76.8)	110 (71.9)	168 (76.4)	216 (80.0)	92 (78.6)	6 (54.6)	0.140α
Age at MS onset, y mean (SD)	31.4 (10.0)	31.8 (10.4)	31.0 (9.8)	30.9 (9.9)	33.1 (9.9)	27.8 (9.4)	0.192β
Age at treatment start, y mean (SD)	36.8 (10.7)	37.6 (11.0)	35.9 (10.6)β	36.0 (10.7)β	39.6 (10.0)β	35.3 (12.4)	0.024β
Disease duration at treatment start, y median (IQR)	2.7 (0.9, 7.7)	2.5 (0.9, 8.4)	2.5 (0.9, 7.0)	2.5 (0.8, 7.1)	3.3 (1.1, 9.2)	6.2 (3.2, 11.5)	0.117γ
EDSS at treatment start median (IQR)	2 (1, 3)	2 (0, 2.5)	2 (1, 3)	2 (1, 3.5)	2 (1, 3)	3 (1.5, 5.5)	0.154γ

Abbreviations: n, number; y, years; SD, standard deviation; IQR, interquartile range; EDSS, Expanded Disability Status Scale.

^αPearson χ² test.

^βOne-way ANOVA with Bonferroni’s post hoc test.

^γKruskal-Wallis rank sum test.