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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: Cancer Res. 2013 Mar 6;73(6):1821–1830. doi: 10.1158/0008-5472.CAN-12-2067

Fig. 1. c-MYC is upregulated in ducal precursor lesions as well as pancreatic ductal adenocarcinomas (PDACs) in humans.

Fig. 1

A. Immunofluorescence staining of c-MYC (red, nuclear) and CK19 (green) in the normal pancreas, pancreatic intraepithelial neoplasia, PanIN (upper panel), and selected pancreatic ductal adenocarcinomas (four lower panels). The AQUA score (AS) in the lower panel is indicative for the intensity of the c-MYC staining pattern; bars represent 50 μm. B. Waterfall plot of AQUA scores (automated quantitative image analysis) of 65 individual PDAC cases