Table 2.
Serovar | MPA (mg/mouse) | IFU/mouse | # of mice shed/Total # mice (%) | # of Fertilea mice/Total # mice (%) | Mean # embryos per uterine hornb
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Right | Leftc | Total | |||||
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D (UW-3/Cx) | 1 | 103 | 9/20 d,e,f (45) | 2/20 d,e,f (10) | 1.5 ± 2.7 g,h | 0.6 ± 1.4 g,i,j | 2.0 ± 3.3 g,h,j |
F (N.I.1) | 1 | 103 | 10/20 d,e,f (50) | 5/20 d,f (25) | 4.4 ± 2.2 i | 0.8 ± 1.4 g,i,j | 5.1 ± 2.6 g |
F (IC-Cal-3) | 1 | 103 | 0/20 | 9/20 d (45) | 2.1 ± 2.4 g | 2.2 ± 2.7 g | 4.3 ± 4.5 g |
SPG | 1 | - | 0/26 | 24/26 (92) | 4.4 ± 1.8 | 4.3 ± 1.5 | 8.7 ± 2.0 |
E (Bour) | 2 | 103 | 1/16 (6) | 11/16 (69) | 3.0 ± 2.6 | 2.9 ± 2.4 | 5.9 ± 4.3 |
SPG | 2 | - | 0/16 | 12/16 (75) | 3.6 ± 2.8 | 2.8 ± 2.0 | 6.4 ± 4.2 |
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D (UW-3/Cx) | 0 | 105 | 14/20 k,l,m,n (70) | 8/20 k,l,m,n (40) | 3.5 ± 2.6 | 2.2 ± 2.1o,p | 5.6 ± 2.8 o,q |
F (N.I.1) | 0 | 105 | 6/20 k,m,n (30) | 1/20 k,m,n (5) | 3.0 ± 2.9 | 0.2 ± 0.7 p,q,r | 3.2 ± 3.1 p,q,r |
F (IC-Cal-3 | 0 | 105 | 0/20 | 16/20 (80) | 4.1 ± 2.4 | 3.4 ± 2.1 | 7.5 ± 4.0 |
E (Bour) | 0 | 105 | 0/16 | 14/16 (88) | 3.8 ± 2.2 | 3.8 ± 1.8 | 7.6 ± 3.2 |
SPG | 0 | - | 0/44 | 37/44 (84) | 3.8 ± 2.3 | 3.2 ± 2.1 | 7.0 ± 3.6 |
Fertility is defined as at least one embryo present in each uterine horn (bilateral)
Values are means ± standard deviations (16–44 animals per group)
Inoculation site
P<0.05 by the Fisher’s Exact test compared to the SPG MPA group
P<0.05 by the Fisher’s Exact test compared to the F (IC-Cal-3) MPA group
P<0.05 by the Fisher’s Exact test compared to the E (Bour) MPA group
P<0.05 by the Student’s t-test compared to the SPG MPA group
P<0.05 by the Student’s t-test compared to the F (N.I.1) MPA group
P<0.05 by the Student’s t-test compared to the F (IC-Cal-3) MPA group
P<0.05 by the Student’s t-test compared to the E (Bour) MPA group
P<0.05 by the Fisher’s Exact test compared to the SPG non-MPA group
P<0.05 by the Fisher’s Exact test compared to the F (N.I.1) non-MPA group
P<0.05 by the Fisher’s Exact test compared to the F (IC-Cal-3) non-MPA group
P<0.05 by the Fisher’s Exact test compared to the E (Bour) non-MPA group
P<0.05 by the Student’s t-test compared to the F (N.I.1) non-MPA group
P<0.05 by the Student’s t-test compared to the E (Bour) non-MPA group
P<0.05 by the Student’s t-test compared to the SPG non-MPA group
P<0.05 by the Student’s t-test compared to the F: IC-Cal-3 0 mg non-MPA group