Table 1.

CD33 SNPs identified by sequencing and genotyped in the present study.

CD33 SNP	rs#	Location	Allele Frequency	Flanking sequence
Leu10Leu	rs117255828	Exon 1	T=0.02	GCTGCCCCTG-C-TGTGGGCAGG
Ala14Val	rs12459419	Exon 2	T=0.31	CCCACAGGGG-C-CCTGGCTATG
Arg62Glu		Exon 2	A=0.005	TACTGGTTCC-G-GGAAGGAGCC
Ala65Pro		Exon 2	C=0.005	CCGGGAAGGA-G-CCATTATATC
Arg69Gly	rs2455069	Exon 2	G=0.4	CCATTATATCC-A-GGGACTCTCC
Phe243Leu	rs11882250	Exon 4	C=0.01	AACTGGTATC-T-TTCCAGGAGA
Val267Ile	rs58981829	Exon 5	A=0.02	AGGAGCTGGT-G-TTACAGCCCT
Arg304Gly	rs35112940	Exon 6	A=0.13	CCCTACCACA-G-GGTCAGCCTC
Ser305Pro	rs61736475	Exon 6	C=0.04	TACCACAGGG-T-CAGCCTCCCC
Ala331Thr	rs35632246	Exon 7	G=0.004	TGCCGCCCCT-A-CTGTGGAGAT
intron 6	rs273621	Intron 6 (Splice site)	C=0.01	GCCTCCCCGG-T-GAGTGATGGG
3′UTR	rs1803254	3′UTR	C=0.22	CATTTGCTAA-G-TGTATGATGT

SNPs in bold occur with minimum allele frequency (MAF) of more than 0.1 were selected for genotyping.