Table 1.
Chitosan | DDA (%) | Mw (kDa) | Mn (kDa) | PDI | Characteristics |
---|---|---|---|---|---|
High (150K) Powder* |
81.8 |
274.6 |
241.2 |
1.1 |
|
High (150K) Solution** |
81.8 |
124.2 |
107.4 |
1.2 |
pH=3.10 Osm=48mosm |
RITC-150K *** |
80.6 |
246.4 |
176 |
1.4 |
0.50% mol/mol RITC/chi |
Low (40K) Powder* |
81.9 |
47.7 |
37.3 |
1.3 |
|
Low (40K) Solution** |
81.9 |
31.6 |
25.3 |
1.2 |
pH=1.65 Osm=72mosm |
RITC-40K *** |
80.6 |
61.5 |
46.7 |
1.3 |
0.52% mol/mol RITC/chi |
Ultralow (10K) Powder* |
81.9 |
22.8 |
10.3 |
2.2 |
|
Ultralow (10K) Solution** |
81.9 |
23.8 |
12.7 |
1.9 |
pH=5.58 Osm=48mosm |
RITC-10K *** | 80.0 | 22.4 | 12.4 | 1.8 | 0.58% mol/mol RITC/chi |
* Chitosan powder used to make the 20 mg/mL autoclave-sterilized solution; ** Autoclaved 20 mg/mL chitosan solution; *** RITC-chitosan powder used to make the 5 mg/mL filter-sterilized solution; DDA: Degree of deacetylation; Mw: Weight-average molecular weight; Mn: Number-average molecular weight; PDI: Polydispersity index (Mw/Mn); Osm: Osmolality; chi: chitosan.