Table 1.
EAE clinical signs in wild-type mice treated with PBS or mAb 1379.
| CDI | Disease Onset | Disease Incidence | ||
|---|---|---|---|---|
| 30 Days PID | PBS-treated n=9 |
57.7 | 13.1d | 100 |
| mAb 1379-treated n=10 |
41.6* | 15.4d | 80 | |
|
| ||||
| 52 Days PID | PBS-treated n=8 |
179 | 9.1d | 100 |
| mAb 1379-treated n=9 |
102* | 13.8d | 89 | |
CDI = cumulative disease index, PI = post-induction of EAE.
Significantly different than PBS-treated controls, p<0.05.