Table 3.
Demographic and clinical features of MDD subgroups [Low anhedonic patients (n= 34) and high anhedonic patients (n= 44)] at baseline.
| Low anhedoniaa | High anhedoniab | Statistics | ||||
|---|---|---|---|---|---|---|
| Mean | SD | Mean | SD | p | ||
| Age | 47.6 | 11.9 | 43.0 | 11.6 | t= 1.7 | 0.1 |
| Gender (female/male) | 17/17 | - | 30/14 | - | χ2=2.3 | 0.1 |
| Anxiety disorder (%)c | 48.6 | - | 50.0 | - | χ2=0.02 | >0.5 |
| Age of onset | 36.8 | 14.0 | 35.0 | 12.2 | t=0.61 | >0.5 |
| Number of episodesd | 2.3 | 1.9 | 2.6 | 2.0 | t=0.64 | >0.5 |
| Medication (YES/NO)e | 33/1 | 42/2 | χ2=0.01 | >0.5 | ||
| HDRS | 14.7 | 4.5 | 18.6 | 4.5 | t=3.8 | 0.01 |
| SHAPS | 4.0 | 2.4 | 9.8 | 1.9 | t=12.0 | <0.01 |
a
Low anhedonia=SHAPS score ≤ 7;
b
High anhedonia=SHAPS > 7.
c
Anxiety disorder= SCID diagnosis of panic disorder and/or agoraphobia, social phobia and/or OCD.
d
Number of episodes= average (Low anhedonia = 35.9% first; 38.5.7% second; 25.6% third or more. High anhedonia = 33.3% first; 26.7% second; 40.0% third or more).
e
Medication: number of patients taking psychopharmacology yes/no (Low anhedonia=35.0% SSRI; 40.0 % SNRI; 25.0 % others. High anhedonia=37.8% SSRI; 35.6 % SNRI; 22.2 % others).
HDRS: Hamilton Depression Rating Scale; SHAPS: Snaith Hamilton Pleasure Scale.