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. Author manuscript; available in PMC: 2014 Jul 1.
Published in final edited form as: Biotechnol Adv. 2013 Jan 26;31(4):438–449. doi: 10.1016/j.biotechadv.2013.01.006

Figure 3.

Figure 3

Design of the diagnostic magnetic resonance (DMR) system (Lee et al., 2008).

(A) Principle of the magnetic particle based proximity assay. Due to the presence of targets, functionalized magnetic nanoparticles aggregate and result in a decrease in spin-spin relaxation time. (B) Schematic of the DMR system. This system includes microcoils for NMR measurements, microfluidic networks for sample preparation, NMR electronics and a magnetic field generated by a permanent magnet. (C) Picture of the microcoil. (D) Image of the microfluidic network. (E) Schematic of the nuclear magnetic resonance circuit.