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. 2013 Mar 19;8(3):e59406. doi: 10.1371/journal.pone.0059406

Figure 9. SiRNA-mediated inhibition of ATG7 expression blocks 2-ME-mediated autophagosome formation.

Figure 9

MG63 osteosarcoma cells were treated with vehicle (Veh), 10 µM 2-ME, 2-ME plus 100 nM ATG7siRNA (ATG7Si) and 2-ME plus 100 nM Non specific siRNA (NSsi) for 48 hrs and analyzed using TEM.