Table 2.
Pooled estimates of the variability (standard deviation, SD) of changes in composite strength scores by study.
Composite MVICT Score | Composite MMT Score | |||||||
---|---|---|---|---|---|---|---|---|
6 months | 12 months | 6 months | 12 months | |||||
n | SD | n | SD | n | SD | n | SD | |
Natural History Study[20] | 48 | 1.23 | 50 | 0.98 | 48 | 0.19 | 47 | 0.23 |
Albuterol RCT[21] | 85 | 1.00 | 84 | 1.04 | 85 | 0.16 | 84 | 0.17 |
MYO-029 RCT[23] | 30 | 1.53 | - | - | 31 | 0.22 | - | - |
Dutch Exercise/Albuterol Study[22] | 64 | 0.71 | 64 | 0.84 | - | - | - | - |
Pooled | 227 | 1.10 | 198 | 0.96 | 164 | 0.18 | 131 | 0.19 |