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. Author manuscript; available in PMC: 2014 Apr 15.
Published in final edited form as: J Neurosci Methods. 2013 Feb 4;214(2):149–155. doi: 10.1016/j.jneumeth.2013.01.024

Figure 2. Optically and electrically induced dopamine release detected by voltammetry.

Figure 2

Striatal dopamine effluxes were evoked by a single pulse (4 ms) of light stimulation (A - in vitro, B - in vivo) and electrical stimulation (C - in vitro). For in vitro experiments the stimulation was locally executed in the dorsal part of striatal slice, while in experiments in vivo the stimulation was applied to the SN of anesthetized rats. Standard two-dimensional color plots topographically depict the voltammetric data with time on the x-axis, applied scan potential on the y-axis, and background-subtracted faradaic current shown in the z-axis in pseudocolor. Representative background-subtracted voltammograms obtained for every signal show typical oxidation and reduction peak potentials (≈ +0.6 V and −0.2 V, respectively) that identify dopamine.