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. 2013 Mar 19;8(3):e58511. doi: 10.1371/journal.pone.0058511

Figure 7. Regulation of EGFR signaling and CI-MPR trafficking were not altered in Snx5-deficient MEFs.

Figure 7

(A–D, F) Western blotting of EGFR and CI-MPR. (A and C) Signaling downstream of EGFR and (B and D) degradation of EGFR were not altered in primary Snx5-/- MEFs (A and B) and primary lung epithelial cells (PLEs) (C and D). (E) Immunocytochemical analysis of CI-MPR. Localization of CI-MPR was not changed in Snx5-deficient MEFs. (F) Relative degradation ratios of CI-MPR protein in Snx5+/+ and Snx5-/- MEFs.