Table 1. Embryonic survival frequency of Snx5+/+, Snx5+/- and Snx5-/- littermates.
Genotype n (%) | ||||
Age of embryos (day) | Snx5+/+ | Snx5+/- | Snx5-/- | Total n |
E14.5 ∼ E16.5 | 33 (20.3) | 88(54.3) | 41(25.3) | 162 |
E17.5 | 18(23.3) | 38(49.3) | 21(27.2) | 77 |
E18.5 | 124(30.2) | 207(50.3) | 80(19.4)* | 411 |
Embryos from timed matings were genotyped on embryonic day 14.5∼16.5, 17.5 and 18.5 day. Fourth columm shows the observed percentage of Snx5-/- mice (the Mendelian percentage is 25%).
Caculated using χ2 test comparing the expected and observed frequency of viable Snx5-/- mice. (P = 0.0089)