Figure 7. Quantification of spine subtypes in the CA1 region of the hippocampus in different apoE mouse models at 19–21 months of age.

(A–H) Averaged densities of stubby (A–B), thin (C–D), mushroom (E–F), and filopodia (G–H) type protrusions in the CA1 region for all genotypes. Values are mean ± SEM, n = 20–33 neurons from 3–5 mice for each group. *p<0.05, **p<0.01, ***p<0.001.