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. 2013 Mar 19;8(3):e59478. doi: 10.1371/journal.pone.0059478

Figure 10. NSE-apoE4, but not apoE4-KI and GFAP-apoE4, mice have decreased total and mushroom spine densities at 7–8 months of age.

Figure 10

(A–C) Quantification of total spine densities in the CA1 subregion of the hippocampus (A), the entorhinal cortex (B), and the auditory cortex (C). (D–F) Averaged densities of mushroom spines in the CA1 subregion of the hippocampus (D), the entorhinal cortex (E), and the auditory cortex (F). Values are mean ± SEM, n = 27–29 neurons from 4–5 mice for each group. *p<0.05, **p<0.01.