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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Aging Cell. 2013 Feb 18;12(2):237–246. doi: 10.1111/acel.12046

Figure 1.

Figure 1

Kaplan-Meier age patterns of the probability of staying free of CVD for carriers (E4) and non-carriers (NoE4) of the APOE e4 allele. (A) and (B) The FHS cohort, examinations (A) 1 and (B) 14. (C) and (D) The FHSO cohort, examinations (C) 1 and (D) 4. N=m/k denotes (m) the total number of carriers and (k) the number of CVD cases among them. Relative risks (RR) were evaluated using the Cox regression model (see Methods) for all subjects (all) and for more homogeneous “younger” (≤75) and “older” (76+) groups with antagonistic risks. The “younger” group was defined as developing CVD in early life or being censored at younger ages (representatively, 75 years and younger at the end of follow up in 2008). The “older” group was defined as developing CVD in late life or being censored at older ages (representatively, 76 years and older at the end of follow up in 2008). Censored individuals are not depicted.