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Group-averaged basal CBF, BOLD, CBF and CMRO2 fMRI responses to forepaw stimulation before and after methylene blue (MB) injection in the same animals (normoxia). Values are in mean ± SEM (N = 10). Forepaw-evoked CBF and BOLD responses were statistically different between pre- and post-MB. * indicates P < 0.05 with paired t-test.
