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Losing of epithelial cells in the transplanted trachea. Epithelial cells are disappeared rapidly due to ischemia-reperfusion injury at early stage (Days 1 to 3 post-tracheal transplantation) in all transplanted trachea. The pseudoepithelial cells are regenerated from days 4 to 7 in all allografts. The second loss of the regenerated epithelium occurred from days 7 to 14 in all of the allografts except in RaG-1 KO mice, which show similar pattern as isograft controls.
