Table 2.

Incident rates and hazard ratios for fatal and non-fatal coronary heart disease events by tertiles of telomere length (in kilo-bases)

	Tertiles of telomere length
	Longest (Reference) (n = 639)	Middle (n = 639)	Shortest (n = 639)
Telomere length (kilo-bases)	5.5 to 8.2	5.0 to < 5.5	4.1 to <5.0
Number of events	35	62	67
Incidence per 1,000 person-years	6.2	11.2	12.2
Hazard ratios (95% CI)
Unadjusted	1.00 (Reference)	1.81 (1.20–2.75)	1.97 (1.31–2.96)
Model 1*	1.00 (Reference)	1.63 (1.08–2.47)	1.22 (0.81–1.83)
Model 2†	1.00 (Reference)	1.64 (1.07–2.50)	1.30 (0.86–1.97)
Model 3‡	1.00 (Reference)	1.63 (1.07–2.51)	1.25 (0.82–1.90)

^*Model 1 includes adjustment for age and sex.

^†Model 2 includes adjustment for covariates in Model 1 plus body mass index, Framingham risk score, use of lipid-lowering medications, and physical activity.

^‡Model 3 includes adjustment for covariates in Model 2 plus ln CRP, ln IL6, and sICAM-1.