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. Author manuscript; available in PMC: 2014 Mar 15.
Published in final edited form as: Cancer Res. 2013 Jan 3;73(6):1733–1741. doi: 10.1158/0008-5472.CAN-12-2384

Figure 2. High levels of PD-1 receptor on TILs from HPV-HNSCC.

Figure 2

A. Representative flow cytometry of CD4+ T cell population expressing PD-1 in various tissues. Summary graph with mean frequency of CD4+PD-1(+) T cells in non-cancerous tonsils and HPV-HNSCC as compared to peripheral blood. B. Similar analysis performed for CD8+PD-1(+) T cell population. The circle on the representative flow data highlights a subpopulation of CD8+ TILs with high levels of PD-1 expression which was not observed in benign tonsils. (•) denotes chronic tonsillitis specimens and (◇) denotes HPV-HNSCC.