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. Author manuscript; available in PMC: 2014 Mar 1.
Published in final edited form as: Biochim Biophys Acta. 2012 Dec 19;1828(3):1159–1168. doi: 10.1016/j.bbamem.2012.12.005

Figure 4. Functionality of combined Trp mutations.

Figure 4

A, Relative resistance of mutant and control strains to 60 µM FK506. Bars indicate the mean relative growth ± SEM of triplicate samples, normalized to Wt, from five independent experiments. B, Relative mating efficiency ± SEM of five independent experiments. (*) indicate samples that are significantly different than Wt (p<0.01). N-triple mutant: W132Y/W158Y/W311Y; Quad mutant: W228F/W311Y/W694L/W1104Y.