Table 1. Bioclinical and periodontal characteristics of the population studied.
| Parameters (units) | Mild to moderate Periodontitis (n = 16) | Severe Periodontitis (n = 16) | Total (n = 32) | |||
| Median | range | median | range | median | range | |
| Age (years) | 45.5 | 31.0–60.0 | 46.0 | 34.0–60.0 | 46.0 | 31.0–60.0 |
| BMI (kg/m2) | 48.1 | 37.0–73.5 | 47.5 | 36.3–60.9 | 47.5 | 36.3–73.6 |
| Females n (%) | 13 (81) | - | 12 (75) | - | 25 (78) | - |
| Diabetes n (%) | 8 (50) | - | 9 (56) | - | 17 (53) | - |
| Smokers n (%)(1) | 10 (62) | - | 5 (41) | - | 15 (47) | - |
| Remaining teeth n | 27 | 10–28 | 26 | 11–28 | 26 | 10–28 |
| PI | 1.0 | 0.3–2.8 | 1.1 | 0.4–2.2 | 1.0 | 0.3–2.8 |
| GI | 1.8 | 1.4–2.9 | 2.1 | 1.0–2.7 | 1.9 | 1.0–2.9 |
| PPD (mm)† | 2.5 | 1.8–2.7 | 2.8 | 2.4–4.5 | 2.6 | 1.8–4.5 |
| CAL (mm)† | 2.6 | 1.8–4.3 | 2.9 | 2.4–5.0 | 2.8 | 1.8–5.0 |
| CRP (mg/l) | 5.0 | 1.0–23.8 | 6.2 | 1.5–62.8 | 5.6 | 1.0–62.8 |
| Orosomucoid (g/l)* | 0.9 | 0.6–1.2 | 1.1 | 0.6–1.3 | 1.0 | 0.6–1.3 |
| Il–6 (pg/ml) | 3.1 | 1.5–28.0 | 3.6 | 1.8–11.5 | 3.3 | 1.5–28.0 |
| Adiponectin ( µg/ml) | 7.7 | 3.1–11.7 | 6.5 | 3.1–10.9 | 7.4 | 3.1–11.7 |
| Leptin (ng/ml) | 46.9 | 15.4–85.0 | 44.3 | 22.7–98.3 | 45.6 | 15.4–98.3 |
The Wilcoxon rank sum test was used to compare medians between groups, and the Fisher exact test to compare proportions. *p<0.05. †p<0.01. PI: Plaque Index, GI: Gingival Index, PPD: Pocket Probing Depth, CAL: Clinical Attachment Loss, CRP: C-Reactive Protein.
(1)
Smoking status: never versus former and current.