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. 2013 Mar 19;8(3):e59185. doi: 10.1371/journal.pone.0059185

Figure 3. Continuous cigarette smoke exposure impairs the establishment of type 1 immunity in the lung of mycobacteria infected mice.

Figure 3

Following the exposure-challenge model described in Figure 2A, we evaluated the impact of cigarette smoke exposure on the establishment of type 1 immune response in the lung of mycobacterial infected mice. The numbers or frequencies of CD4+ and CD4+IFN-γ+ T cells were evaluated in the airway lumen (A/B/C), and the lung interstitium (D/E/F). The levels of RANTES were assessed in bronchoalveolar lavage fluids (BALFs) (G). Values represent the mean and standard error for 5 mice per exposure protocol. The dotplots are representative images from their respective groups. *p≤0.05; **p≤0.01; ***p≤0.001.