Table 5.

Meta-regression analysis of histologic parameters between adenocarcinoma and squamous cell carcinoma patients according to the published studies (the random effects model was used)

Comparison of ADC vs SCC	Coefficient	95%CI	P value	Better status
Positive lymph nodes	1.890	0.3945146, 3.384624	< 0.01	ADC
Lymphovascular invasion	0.626	-0.7032339, 1.956155	0.340	None
Microvascular invasion	1.114	-0.2682334, 2.496538	0.108	None
Grade 3	0.305	-1.584654, 2.195142	0.731	None

SCC: Squamous cell carcinoma; ADC: Adenocarcinoma.