Table 3.
Long-term outcomes following middle segmental pancreatectomy, pancreaticoduodenectomy and extended distal pancreatectomy n (%)
Variable | PD (n = 42) | MSP (n = 36) | EDP (n = 23) | P value | |
PD vs MSP | MSP vs EDP | ||||
Exocrine and endocrine function | |||||
New-onset DM | 6 (14.3) | 1 (2.8) | 5 (21.7) | NS | 0.029 |
NIDDM | 4 | 1 | 3 | ||
IDDM | 2 | 0 | 2 | ||
Enzyme substitution | 14 (33.3) | 0 | 5 (21.7) | < 0.001 | 0.007 |
Anorexia | 9 (21.4) | 3 (8.3) | 1 (4.3) | NS | NS |
Nausea and vomiting | 5 (11.9) | 2 (5.6) | 0 | NS | NS |
Abdominal distention and diarrhea | 16 (38.1) | 3 (8.3) | 2 (8.7) | 0.005 | NS |
Tumor recurrence | 0 | 0 | 0 | ||
Body weight change1 | |||||
Weight gain | 16 | 15 | 8 | ||
No change | 14 | 12 | 8 | NS | NS |
Weight reduction | 12 | 9 | 7 |
Wilcoxon rank sum test. DM: Diabetes mellitus; NIDDM: Non insulin dependent diabetes mellitus; IDDM: Insulin dependent diabetes mellitus; MSP: Middle segmental pancreatectomy; PD: Pancreaticoduodenectomy; EPD: Extended distal pancreatectomy; NS: Not significant.