Table 2.
Central composite rotatable design (CCRD) and responses
| RUN | Independent variables | Responses (Y) | |||
|---|---|---|---|---|---|
| Temperature (°C) | Mass fraction of the β-cyclodextrin (%) | Incubation time (min) | Y1 (Bitterness) | Y2 (OD700 nm) | |
| 1 | −1 | −1 | −1 | 4.0 | 0.427 |
| 2 | −1 | −1 | 1 | 3.0 | 0.435 |
| 3 | −1 | 1 | −1 | 2.0 | 0.447 |
| 4 | −1 | 1 | 1 | 2.0 | 0.454 |
| 5 | 1 | −1 | −1 | 3.0 | 0.420 |
| 6 | 1 | −1 | 1 | 2.0 | 0.432 |
| 7 | 1 | 1 | −1 | 2.0 | 0.440 |
| 8 | 1 | 1 | 1 | 1.0 | 0.439 |
| 9 | −1.682 | 0 | 0 | 4.0 | 0.447 |
| 10 | 1.682 | 0 | 0 | 2.0 | 0.435 |
| 11 | 0 | −1.682 | 0 | 2.0 | 0.422 |
| 12 | 0 | 1.682 | 0 | 0.0 | 0.459 |
| 13 | 0 | 0 | −1.682 | 2.0 | 0.424 |
| 14 | 0 | 0 | 1.682 | 1.0 | 0.442 |
| 15 | 0 | 0 | 0 | 1.0 | 0.446 |
| 16 | 0 | 0 | 0 | 2.0 | 0.439 |
| 17 | 0 | 0 | 0 | 1.0 | 0.449 |
| 18 | 0 | 0 | 0 | 1.0 | 0.446 |
| 19 | 0 | 0 | 0 | 1.0 | 0.438 |
| 20 | 0 | 0 | 0 | 1.0 | 0.445 |
| 21 | 0 | 0 | 0 | 1.0 | 0.437 |
| 22 | 0 | 0 | 0 | 1.0 | 0.443 |
| 23 | 0 | 0 | 0 | 1.0 | 0.443 |