Skip to main content
. 2013 Mar 19;8(3):e59142. doi: 10.1371/journal.pone.0059142

Figure 1. Analysis of EGFP expression after transduction of HEK293 cells with individual site-directed AAV2 capsid mutants.

Figure 1

Each of the 17 surface-exposed threonine (T) residues in AAV2 capsid was substituted with valine (V) and evaluated for its efficiency to mediate transgene expression. (a) EGFP expression analysis at 48 h post-infection at MOI of 1×103 vg/cell. (b) Quantification of transduction efficiency of each of the threonine-mutant scAAV2 vectors. *P<0.005, **P<0.001 vs. WT AAV2.