Fig. 10.

Rat preglomerular vascular smooth muscle cells were incubated with adenosine (3 μmol/l) for 1 h in the absence or presence of guanosine (30 μmol/l) and either without or with the following: pentostatin (300 μmol/l; adenosine deaminase inhibitor; A) or low sodium in medium (B and C). The medium was assayed for adenosine or adenosine and inosine by mass spectrometry. Values represent means ± SE. ^aSignificantly different from corresponding no-guanosine group; ^bsignificantly different from normal sodium-guanosine group; ^csignificantly different from PBS-no-guanosine group.