Fig. 11.

Rat preglomerular vascular smooth muscle cells were incubated with adenosine (3 μmol/l) for 1 h in the absence or presence of guanosine (30 μmol/l) and either without or with the following: zidovudine (AZT; 2 mmol/l; ENT2 inhibitor; A) or no-sodium buffer (B) or AZT plus NBMPR in a no-sodium buffer (C). The medium was assayed for adenosine by mass spectrometry. Values represent means ± SE. ^aSignificantly different from corresponding no-guanosine group; ^bsignificantly different from normal sodium-guanosine group.