Table 7.
Ames test results of mice (revertant colonies)
|
Dose (mg/plate) |
|
Strains |
|||
|---|---|---|---|---|---|
| TA97 | TA98 | TA100 | TA102 | ||
| 0.1 |
-S9 |
129.3 ± 11.4 |
32.3 ± 6.7 |
134.7 ± 20.0 |
290.0 ± 33.4 |
| |
+S9 |
128.7 ± 25.0 |
38.0 ± 6.9 |
138.3 ± 13.2 |
294.0 ± 28.0 |
| 0.05 |
-S9 |
128.7 ± 15.1 |
33.0 ± 7.8 |
132.0 ± 16.0 |
279.3 ± 22.0 |
| |
+S9 |
139.3 ± 8.3 |
35.7 ± 5.5 |
132.0 ± 18.3 |
295.7 ± 14.4 |
| 0.025 |
-S9 |
131.3 ± 9.0 |
33.0 ± 7.2 |
128.7 ± 12.2 |
280.0 ± 13.1 |
| |
+S9 |
142.0 ± 11.1 |
40.0 ± 5.3 |
151.0 ± 13.5 |
302.3 ± 19.3 |
| 0.0125 |
-S9 |
118.0 ± 13.5 |
33.3 ± 6.4 |
127.7 ± 19.7 |
279.3 ± 28.4 |
| |
+S9 |
121.3 ± 11.0 |
34.0 ± 6.5 |
134.7 ± 16.2 |
284.3 ± 17.6 |
| Negative control |
-S9 |
135.3 ± 14.7 |
31.0 ± 4.6 |
136.7 ± 24.4 |
294.0 ± 27.5 |
| |
+S9 |
131.0 ± 26.5 |
41.0 ± 4.0 |
130.7 ± 18.0 |
288.7 ± 20.4 |
| Positive solvent group |
-S9 |
130.3 ± 14.6 |
33.7 ± 4.2 |
- |
284.0 ± 20.3 |
| |
+S9 |
130.7 ± 12.1 |
34.7 ± 6.1 |
137.3 ± 13.3 |
295.3 ± 21.4 |
| Positive control |
-S9 |
803.3 ± 165.0 |
893.3 ± 220.3 |
640.0 ± 91.7 |
946.7 ± 122.2 |
| +S9 | 780.0 ± 177.8 | 1,160.0 ± 183.3 | 746.7 ± 140.5 | 1,000.0 ± 208.8 | |