Fig. 5.

Autoregulation of renal blood flow (RBF) in vivo. Autoregulation of RBF in anesthetized rats from control (white circles), ANG II alone (60 ng/min, gray triangles), and ANG II + MMF (30 mg·kg⁻¹·day⁻¹, black squares). A: actual RBF against mean arterial pressure (MAP). B: normalized RBF as percent of baseline RBF against MAP. Numbers above or below each symbol indicate the animal number studied at each level of MAP. Each point represents the means ± SE. *P < 0.05 vs. baseline RBF in same group. †P < 0.05, significant difference between ANG II and ANG II + MMF groups. C: autoregulatory index over the range from initial arterial pressure to 100 and 70–90 mmHg, respectively. †P < 0.05 vs. control rats. #P < 0.05 vs. ANG II alone.