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Diabetes increases expression of proinflammatory proteins in ischemic AKI. The db/db and db/+ mice were subjected to 20 min of bilateral renal ischemia or sham surgery. Kidneys harvested 24 h after surgery were used for real-time RT-PCR quantitation of mRNA. Data are expressed as fold changes relative to control kidneys from mice of the same strain. *P < 0.05 vs. sham surgery; n = 3–5.
