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TNF-α neutralization reduces renal ischemic injury in diabetic mice. The db/db mice were injected with goat IgG or goat anti-mouse TNF-α antibody and then subjected to 20 min of bilateral renal ischemia. +P < 0.01 vs. db/+; *P < 0.01 vs. db/db + IgG; n = 4–5.
