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. 2013 Mar 19;104(6):1221–1229. doi: 10.1016/j.bpj.2013.02.009

Figure 6.

Figure 6

The ratio between the equilibrium constants of reaction 1 in the 2D and 3D environment, λ=Kd(2D)/Kd(3D), as a function of the angular allowance ΔΩ. (Circles) Results of the dynamic Monte Carlo simulations. (Triangles) Results obtained using Eq. 5, with molecular parameters (hi, Δωi) derived from the IMC simulations of structural fluctuations of immobile receptors.