Fig. 2.

Genotype-specific differences in postsurgical (at 24 h) distal limb perfusion and perfused sites were detected only after severe, not mild, surgery. A: distal limb perfusion in Cx40^−/− vs. WT differed (*) 24 h after severe surgery [P < 0.02; WT: n = 9 (5 male); Cx40^−/−: n = 10 (4 male)] but not mild surgery [P = 0.58; WT: n = 18 (13 male); Cx40^−/−: n = 16 (9 male)]. B: flow (intensity) 24 h after both surgery types did not differ in a genotype-specific manner (severe: P = 0.44; mild: P = 0.98). C: number of sites with detectable flow was significantly (*) less in Cx40^−/− than WT mice after severe surgery (P < 0.005) but not after mild surgery (P = 0.072).