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A and B: contractile responses of mesenteric Kcnma1+/+ (A) and C57BL/6J (B) arteries to cumulative concentrations of norepinephrine (NE). PVAT, perivascular adipose tissue; KPSS, high-potassium physiological saline solution. C: solution transfer experiments. D: C57BL/6J arteries in the presence of adiponectin blocking peptide. E: response to exogenous adiponectin in the presence (+E) and absence (−E) of endothelium. F: adipo−/− arteries. *P < 0.05 ANOVA.
