Table 1.
Hemodynamic responses induced by stellate ganglia stimulation
Baseline | LSG Stimulation | RSG Stimulation | BSG Stimulation | |
---|---|---|---|---|
Heart rate, beats/min | 77.6 ± 3.8 | 86.7 ± 8.6 | 134.1 ± 6.6*† | 102.5 ± 5.8* |
End-systolic volume, ml | 23.9 ± 2.2 | 13.2 ± 1.7* | 12.8 ± 1.4* | 12.7 ± 1.3* |
End-diastolic volume, ml | 50.5 ± 4.2 | 43.5 ± 4.3* | 37.6 ± 5.7* | 39.9 ± 2.3* |
Stroke volume, ml | 26.2 ± 2.3 | 30.1 ± 2.5* | 25.3 ± 1.9 | 28.3 ± 1.0 |
Cardiac output, liters | 2.04 ± 0.27 | 2.61 ± 0.28* | 3.39 ± 0.31*† | 2.90 ± 0.30* |
Ejection fraction, % | 51.8 ± 5.3 | 68.5 ± 4.4* | 67.3 ± 5.9* | 69.3 ± 2.74* |
LV end-systolic pressure, mmHg | 83.1 ± 5.3 | 102.7 ± 8.8* | 105.9 ± 5.1* | 114.0 ± 4.3* |
LV End-diastolic pressure, mmHg | 4.6 ± 0.6 | 4.9 ± 0.5 | 4.0 ± 0.5 | 3.5 ± 0.2 |
Total peripheral resistance, mmHg/l | 1,876 ± 120 | 1,988 ± 115 | 1,332 ± 101*† | 2,044 ± 90 |
Stroke work, mmHgml | 2,174 ± 335 | 3,091 ± 341* | 2,679 ± 221*† | 3,226 ± 382* |
dP/dtmax, mmHg/s | 1,612 ± 150 | 4,296 ± 230* | 4,518 ± 297* | 5,057 ± 241*† |
dP/dtmin, mmHg/s | 1,564 ± 160 | 3,782 ± 256* | 3,922 ± 211* | 4,196 ± 243*† |
τ, ms | 69.2 ± 4.8 | 54.8 ± 5.9* | 56.9 ± 3.2* | 51.7 ± 4.0* |
End-diastolic volume/LV end-diastolic pressure, ml/mmHg | 11.0 ± 2.3 | 8.7 ± 1.8 | 9.4 ± 2.1 | 11.4 ± 2.6† |
Values are means ± SD. LSG, left stellate ganglion; RSG, right stellate ganglion; BSG, bilateral stellate ganglia; LV, left ventricular; dP/dtmax and dP/dtmin, maximum positive and negative rates of pressure change, respectively; τ, time constant of isovolumic relaxation.
P < 0.05 vs. baseline;
P < 0.05 vs. LSG stimulation.