Table 1.
Features of GHD adult patients |
---|
Reduced lean body mass and increased visceral adiposity |
Reduced bone mineral density with increased risk of fractures |
Reduced IGF-I levels |
Decreased muscle strength and exercise capacity |
Diminished quality of life (less cognitive function, decreased of well-being) |
Abnormal serum lipid profile (increased total cholesterol, LDL cholesterol, triglycerides, lipoprotein A, apolipoprotein B; decreased HDL cholesterol) |
Lower cardiac function, impaired left ventricular performance, and increased prevalence of cardiovascular disease |