Table 2.
Treatment |
pH | PO2, mmHg | PCO2, mmHg | HR, beats/min | MAP, mmHg | Weight, kg |
---|---|---|---|---|---|---|
Control (saline) | 7.36 ± 0.01 | 23.36 ± 1.15 | 53.88 ± 1.11 | 137.1 ± 4.8 | 44.1 ± 0.4 | 4.38 ± 0.76 |
Control (LA) | 7.34 ± 0.01 | 22.00.±1.10 | 54.0 ± 1.17 | 142.4 ± 4.0 | 42.5 ± 0.5 | 4.04 ± 0.40 |
LTH (saline) | 7.37 ± 0.01 | 18.63 ± 1.19* | 43.70 ± 1.45* | 145.5 ± 1.7 | 43.2 ± 0.6 | 3.69 ± 0.02 |
LTH (LA) | 7.38 ± 0.01 | 19.54 ± 0.58* | 44.86 ± 1.47* | 140.3 ± 3.3 | 43.2 ± 0.6 | 4.05 ± 0.15 |
Values are means ± SE. LA, leptin antagonist; HR, heart rate; MAP, mean arterial pressure.
P < 0.05 compared with control.