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. 2012 Dec 5;109(5):1333–1342. doi: 10.1152/jn.00350.2012

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Fig. 8. — Parallel fiber LTD (paired PF activation and Purkinje cell depolarization) is not impaired by ethanol. A: typical traces. Top: PF-EPSCs before (black traces) and after tetanization (grey traces) under control conditions. Bottom: PF-EPSCs before and after tetanization in the presence of 10 mM EtOH. The LTD protocol consisted of pairing depolarizing voltage steps (−75 to 0 mV; 250 ms) with 2 PF stimuli (10-ms interval) at 1 Hz for 3 min (repeated once after 5 min). B: time graph showing LTD induced under control conditions (n = 7) and in the presence of 10 mM EtOH (n = 8). Arrows indicate the time points of tetanization. Error bars are mean ± SE.