Table 2. Resistance to gentamicin, kanamycin and amikacin in Shigella spp. collected during 1999-2010.
Antibiotic | Study period | Europe-America |
Asia-Africa |
||||
No. of studies | Resistancet rate%(95%CI) | %Weight | No. of studies | Resistancet rate%(95%CI) | %Weight | ||
Gentamicin | 1999-2001 | 5 | 0.84 (0.08-2.40) | 19.76 | 22 | 6.05 (1.18-14.28) | 21.84 |
2002-2004 | 9 | 0.75 (0.19-1.67) | 33.58 | 37 | 10.17 (6.71-14.21) | 37.84 | |
2005-2007 | 9 | 0.72 (0.35-1.23) | 33.82 | 34 | 12.77 (8.82-17.38) | 32.60 | |
2008-2010 | 3 | 0.25 (0.04-0.64) | 12.85 | 8 | 20.83 (12.67-30.40) | 7.71 | |
Overall | 26 | 0.68 (0.39-1.05) | 100.00 | 101 | 10.81 (8.34-13.52) | 100.00 | |
Kanamycin | 1999-2001 | 4 | 0.87 (0.45-1.42) | 21.26 | 10 | 20.96 (3.37-48.11) | 44.45 |
2002-2004 | 6 | 0.64 (0.19-1.33) | 32.19 | 9 | 14.00 (3.97-28.85) | 39.61 | |
2005-2007 | 6 | 0.58 (0.14-1.28) | 31.55 | 3 | 32.40 (17.87-48.91) | 15.94 | |
2008-2010 | 2 | 0.47 (0.20-0.85) | 15.00 | 0 | N/A | N/A | |
Overall | 18 | 0.60 (0.37-0.88) | 100.00 | 22 | 19.63 (11.85-28.80) | 100.00 | |
Amikacin | 1999-2001 | 4 | 0.28 (0.00-1.08) | 31.69 | 10 | 6.39 (1.40-14.63) | 21.41 |
2002-2004 | 4 | 0.25 (0.00-1.01) | 33.34 | 18 | 9.25 (4.83-14.88) | 41.56 | |
2005-2007 | 3 | 0.06 (0.00-0.26) | 25.58 | 16 | 8.54 (3.70-15.16) | 34.77 | |
2008-2010 | 1 | 0.05 (0.04-0.40) | 9.38 | 1 | 48.06 (34.57-61.65) | 2.26 | |
Overall | 12 | 0.16 (0.03-0.40) | 100.000 | 45 | 8.90 (6.00-12.34) | 100.000 |
N/A: results not available.