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. 2013 Feb 28;27(2):103–115. doi: 10.7555/JBR.27.20120125

Table 2. Resistance to gentamicin, kanamycin and amikacin in Shigella spp. collected during 1999-2010.

Antibiotic Study period Europe-America
Asia-Africa
No. of studies Resistancet rate%(95%CI) %Weight No. of studies Resistancet rate%(95%CI) %Weight
Gentamicin 1999-2001 5 0.84 (0.08-2.40) 19.76 22 6.05 (1.18-14.28) 21.84
2002-2004 9 0.75 (0.19-1.67) 33.58 37 10.17 (6.71-14.21) 37.84
2005-2007 9 0.72 (0.35-1.23) 33.82 34 12.77 (8.82-17.38) 32.60
2008-2010 3 0.25 (0.04-0.64) 12.85 8 20.83 (12.67-30.40) 7.71
Overall 26 0.68 (0.39-1.05) 100.00 101 10.81 (8.34-13.52) 100.00
Kanamycin 1999-2001 4 0.87 (0.45-1.42) 21.26 10 20.96 (3.37-48.11) 44.45
2002-2004 6 0.64 (0.19-1.33) 32.19 9 14.00 (3.97-28.85) 39.61
2005-2007 6 0.58 (0.14-1.28) 31.55 3 32.40 (17.87-48.91) 15.94
2008-2010 2 0.47 (0.20-0.85) 15.00 0 N/A N/A
Overall 18 0.60 (0.37-0.88) 100.00 22 19.63 (11.85-28.80) 100.00
Amikacin 1999-2001 4 0.28 (0.00-1.08) 31.69 10 6.39 (1.40-14.63) 21.41
2002-2004 4 0.25 (0.00-1.01) 33.34 18 9.25 (4.83-14.88) 41.56
2005-2007 3 0.06 (0.00-0.26) 25.58 16 8.54 (3.70-15.16) 34.77
2008-2010 1 0.05 (0.04-0.40) 9.38 1 48.06 (34.57-61.65) 2.26
Overall 12 0.16 (0.03-0.40) 100.000 45 8.90 (6.00-12.34) 100.000

N/A: results not available.