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. Author manuscript; available in PMC: 2014 Apr 1.
Published in final edited form as: Eur J Oral Sci. 2013 Feb 7;121(2):76–85. doi: 10.1111/eos.12020

Figure 8. Biglycan immunostaining of predentin in 3-month-old mice.

Figure 8

The WT mice (A) showed a narrow predentin zone demarcated by the brown positive biglycan staining. In the Dspp KO mice (B), anti-biglycan activity revealed a widened predentin layer and an irregular dentin-predentin border as compared to the WT mice (A). The results from the Dspp KO/DSP Tg mice (C) indicated that nearly the entire predentin-dentin complex in these mice was made of the unmineralized predentin with anti-biglycan staining extending and covering most of the structure. Bar: A-H = 100 μm.