Table 5.
Age- and Multivariable-Adjusted Odds Ratios for County Sociodemographic Variables and Clinical Treatment Trial Accrual in Maryland, 1999 to -2002
| County Variable | Female | Male | ||||||
|---|---|---|---|---|---|---|---|---|
|
| ||||||||
| Percentage Accrued | Age-Adjusted | Adjusted* | Percentage Accrued |
Age-Adjusted | Adjusted* | |||
|
| ||||||||
| n | % | OR (95% CI) | OR (95% CI) | n | % | OR (95% CI) | OR (95% CI) | |
|
Material Deprivation Summary Score |
||||||||
| Quartile 1 | 195 | 2.91 | 1.00 | 1.00 | 110 | 1.48 | 1.00 | 1.00 |
| Quartile 2 | 527 | 3.22 | 0.79 (0.51-1.23) | 0.76 (0.50-1.15) | 340 | 1.67 | 1.05 (0.81-1.36) | 1.03 (0.81-1.30) |
| Quartile 3 | 367 | 2.14 | 0.72 (0.46-1.14) | 0.66 (0.42-1.04) | 238 | 1.47 | 0.95 (0.72-1.27) | 0.91 (0.71-1.18) |
| Quartile 4 | 223 | 1.58 | 0.34 (0.19-0.60) | 0.45 (0.23-0.89) | 225 | 1.62 | 0.71 (0.49-1.03) | 0.83 (0.49-1.40) |
| p for trend | <0.001 | <0.001 | <0.001 | <0.001 | ||||
|
| ||||||||
|
Social
Class Summary Score |
||||||||
| Quartile 1 | 102 | 1.67 | 1.00 | 1.00 | 120 | 1.46 | 1.00 | 1.00 |
| Quartile 2 | 91 | 2.29 | 2.16 (1.01-4.61) | 1.60 (0.86-2.98) | 65 | 1.44 | 1.46 (0.97-2.20) | 1.31 (0.87-1.99) |
| Quartile 3 | 558 | 2.73 | 2.67 (1.86-3.84) | 2.12 (1.82-2.46) | 359 | 1.50 | 1.44 (1.13-1.82) | 1.34 (1.15-1.56) |
| Quartile 4 | 561 | 3.15 | 3.01 (2.21-4.12) | 2.29 (1.84-2.83) | 369 | 1.85 | 1.71 (1.38-2.11) | 1.57 (1.32-1.86) |
| p for trend | 0.018 | 0.011 | <0.001 | <0.001 | ||||
|
| ||||||||
|
Percent Non-
White ** |
||||||||
| Quartile 1 | 141 | 2.57 | 1.00 | 1.00 | 92 | 1.25 | 1.00 | 1.00 |
| Quartile 2 | 302 | 2.64 | 1.20 (0.70-2.07) | 1.19 (0.69-2.04) | 174 | 1.59 | 1.09 (0.83-1.44) | 1.08 (0.83-1.42) |
| Quartile 3 | 396 | 2.23 | 1.01 (0.57-1.76) | 1.02 (0.59-1.75) | 260 | 1.70 | 1.14 (0.86-1.51) | 1.15 (0.86-1.53) |
| Quartile 4 | 473 | 2.34 | 0.66 (0.31-1.38) | 0.67 (0.33-1.38) | 387 | 1.71 | 0.95 (0.65-1.39) | 0.97 (0.66-1.40) |
| p for trend | 0.001 | 0.001 | 0.001 | 0.001 | ||||
|
| ||||||||
| Percent Rural *** | ||||||||
| Quartile 1 | 981 | 2.82 | 1.00 | 1.00 | 698 | 1.94 | 1.00 | 1.00 |
| Quartile 2 | 174 | 2.27 | 1.28 (0.86-1.91) | 1.06 (0.66-1.68) | 112 | 1.41 | 0.98 (0.78-1.24) | 0.90 (0.69-1.17) |
| Quartile 3 | 105 | 2.54 | 1.50 (1.02-2.23) | 1.21 (0.81-1.80) | 69 | 1.56 | 1.10 (1.02-1.19) | 1.01 (0.89-1.15) |
| Quartile 4 | 52 | 2.22 | 1.24 (1.04-1.49) | 1.03 (0.87-1.21) | 34 | 1.34 | 0.93 (0.70-1.23) | 0.85 (0.63-1.15) |
| p for trend | 0.124 | 0.456 | 0.295 | 0.809 | ||||
|
| ||||||||
|
ACOS Approved Hospitals |
~ | ~ | 1.02 (0.79-1.31) | 0.91 (0.80-1.02) | ~ | ~ | 1.01 (0.91-1.12) | 0.95 (0.88-1.04) |
|
| ||||||||
| Oncologists | ~ | ~ | 0.93 (0.73-1.17) | 0.96 (0.87-1.06) | ~ | ~ | 1.03 (0.91-1.16) | 1.04 (0.98-1.12) |
OR=Odds Ratio and CI= Confidence Interval; %=number of trial participants/number of cancer cases*100
Models are adjusted for racial composition of county, age distribution of clinical trials patients, and rural classification of counties.
Adjusted model is adjusted for age distribution of clinical trials patients and the rural classification of counties.
Adjusted model is adjusted for racial composition of county and age distribution of clinical trials patients.
NOTE: Material deprivation measures include percent of: persons living in poverty, households without a car, unemployed persons age 16 and older, and owner-unoccupied housing. Social class summary score includes percent of: high school graduates among persons 25 and older, persons with graduate or professional degrees, persons employed in white collar jobs, and median household income.