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. Author manuscript; available in PMC: 2013 Mar 20.
Published in final edited form as: Toxicol Appl Pharmacol. 2009 Jan 7;235(3):321–328. doi: 10.1016/j.taap.2008.12.022

Figure 5.

Figure 5

STAT-3 activation is induced by 3,6-BPQ but not by 1,6-BPQ and EGF in MCF-10A cells. Cells were treated with 1 μM BPQs or 10 ng/ml EGF for 18 hr and 10 ng/ml EGF for 15 min. Whole cell lysates (80 μg) were used for Western blot analysis and detected with anti-phosphorylated STAT-3, stripped and reprobed with anti STAT-3 and actin antibodies. 3,6-BPQ induced STAT-3 activation to the same extent as EGF (15 min). Statistical analyses are for this individual experiment. Bars show the means ± S.E. * p<0.05 as compared with control.