Table 1.
Sjögren (n = 24) | Controls (n = 24) | ||||||
---|---|---|---|---|---|---|---|
Clinical data | |||||||
Sicca | 24 (8 = IV, 5 = III, 6 = II, 5 = I) | 0 | *P < 0.0001 | ||||
Glandular | 24 (8 = IV, 5 = III, 6 = II, 5 = I) | 0 | *P < 0.0001 | ||||
Extraglandular | 10 (8 = IV, 2 = III) | 0 | *P < 0.0006 | ||||
| |||||||
Serology | |||||||
Anti-CCP | 2 (2 = IV) | 0 | *P < 0.4890 | ||||
+RF | 10 (8 = IV, 2 = III) | 0 | *P < 0.0006 | ||||
+ANA | 16 (8 = IV, 5 = III, 3 = II) | 0 | *P < 0.0001 | ||||
+Anti-La | 12 (7 = IV, 4 = III, 1 = II) | 0 | *P < 0.0025 | ||||
+Anti-Ro | 14 (8 = IV, 4 = III, 1 = II, 1 = I) | 0 | *P < 0.0001 | ||||
| |||||||
Biopsies | |||||||
Acini | Ducts | Infiltrates | Acini | Ducts | Infiltrates | ||
| |||||||
PAD 2 | 17 £(8 = IV, 6 = III, 2 = II, 1 = I) |
17 £(8 = IV, 6 = III, 2 = II, 1 = I) |
12 £(8 = IV, 4 = III) |
0 | 2 | 0 | *P < 0.0001 |
CCP | 17 £(8 = IV, 5 = III, 3 = II, 1 = I) |
17 £(8 = IV, 5 = III, 3 = II, 1 = I) |
17 £(8 = IV, 5 = III, 3 = II, 1 = I) |
0 | 0 | 0 | *P < 0.0001 |
Citrulline | 19 £(8 = IV, 5 = III, 5 = II, 1 = I) |
19 £(8 = IV, 5 = III, 5 = II, 1 = I) |
17 £(8 = IV, 5 = III, 3 = II, 1 = I) |
0 | 2 | 0 | *P < 0.0001 |
*Sjögren versus controls.
£Sjögren class IV versus class I = P < 0.003.
Histology class inside the parentheses.