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. 2013 Feb 22;2(1):e004713. doi: 10.1161/JAHA.112.004713

Figure 2.

Figure 2.

Steady‐state Ca2+ dependency of IKAS in non‐HF and HF ventricular myocytes. IKAS was normalized to the maximal IKAS with a free Ca2+ of 10 μmol/L and plotted as a function of Ca2+ concentration. The data were fitted with Hill equation: y=1/(1+[Kd/x]n), where y indicates the normalized IKAS and x is the intrapipette free calcium; Kd is the concentration of intrapipette free calcium at half‐maximal activation of IKAS; and n is the Hill coefficient. Error bars represent SEM. Numbers in parentheses indicate the number of cells patched. Normalized currents were presented as mean±SEM. HF indicates heart failure.