Table 4.
Region | N | i‐TTR, mean % | SD | Median (25th, 75th) | Parameter Estimate | P Value |
---|---|---|---|---|---|---|
East Asia | 677 | 53.3 | 21.7 | 56 (40, 67) | −12.52 | <0.0001 |
India | 115 | 39.5 | 25.2 | 42 (21, 56) | −26.38 | <0.0001 |
Eastern Europe | 2462 | 53.0 | 21.5 | 55 (40, 68) | −12.82 | <0.0001 |
Western Europe/similar | 1019 | 66.6 | 17.7 | 69 (58, 79) | 0.76 | 0.37 |
South Africa | 115 | 57.6 | 21.1 | 59 (46, 74) | −8.19 | <0.0001 |
Latin America | 875 | 59.0 | 20.0 | 61 (48, 74) | −6.84 | <0.0001 |
Canada/United States | 1244 | 65.8 | 18.7 | 68 (56, 79) | Ref |
i‐TTR indicates individual patient‐level time in therapeutic range.