Table 1.
Characteristics Analyzed for Development of Dynamic TIMI Risk Score for STEMI
| Characteristics | Univariate Analysis | Multivariable Analysis | ||||
|---|---|---|---|---|---|---|
| β Coefficient | P Value | OR (95% CI) | β Coefficient | P Value | OR (95% CI) | |
| Baseline TIMI risk score for STEMI | ||||||
| Age, y | ||||||
| 65 to 74 | 0.98 | <0.001 | 2.57 (2.31 to 3.10) | |||
| >75 | 1.61 | <0.001 | 5.04 (4.32 to 5.90) | |||
| Diabetes mellitus | 0.70 | <0.001 | 2.01 (1.74 to 2.33) | |||
| Hypertension | 0.71 | <0.001 | 2.04 (1.80 to 2.32) | |||
| Angina | 0.80 | <0.001 | 2.22 (1.97 to 2.53) | |||
| SBP <100 | 0.57 | <0.001 | 1.76 (1.34 to 2.31) | |||
| Heart rate >100 | 1.05 | <0.001 | 2.84 (2.39 to 3.39) | |||
| Killip class II to IV | 1.06 | <0.001 | 2.90 (2.50 to 3.35) | |||
| Weight <67 kg | 0.40 | <0.001 | 1.49 (1.29 to 1.71) | |||
| Anterior STE or LBBB | 0.42 | <0.001 | 1.51 (1.34 to 1.72) | |||
| Time to rx >4 hours | 0.07 | <0.001 | 1.08 (1.06 to 1.10) | |||
| Added index hospital events for dynamic score | ||||||
| Recurrent MI | 0.47 | 0.003 | 1.60 (1.18 to 2.19) | 0.34 | 0.04 | 1.40 (1.01 to 1.94) |
| Stroke | 2.29 | <0.001 | 9.83 (7.33 to 13.20) | 1.59 | <0.001 | 4.90 (3.30 to 7.26) |
| CHF/shock | 1.94 | <0.001 | 6.95 (5.67 to 8.52) | 1.16 | <0.001 | 3.19 (2.53 to 4.01) |
| Major bleed | 1.48 | <0.001 | 4.39 (3.22 to 5.98) | 0.34 | 0.09 | 1.41 (0.94 to 2.10) |
| Arrhythmia | 0.81 | <0.001 | 2.25 (1.88 to 2.69) | 0.47 | <0.001 | 1.60 (1.32 to 1.94) |
| Renal failure | 2.28 | <0.001 | 9.73 (4.85 to 19.52) | 0.95 | 0.01 | 2.59 (1.22 to 5.50) |
| CABG | −0.23 | 0.640 | 0.80 (0.30 to 2.09) | |||
| Recurrent ischemia | 0.40 | 0.005 | 1.49 (1.13 to 1.97) | |||
| Urgent revasc | −0.04 | 0.853 | 0.96 (0.60 to 1.53) | |||
| PCI | −0.09 | 0.604 | 0.91 (0.65 to 1.28) | |||
TIMI indicates thrombolysis in myocardial infarction; STEMI, ST‐elevation myocardial infarction; OR, odds ratio; CI, confidence interval; SBP, systolic blood pressure; STE, ST‐elevation; LBBB, left bundle branch block; rx, treatment; MI, myocardial infarction; CHF, congestive heart failure; CABG, coronary artery bypass graft; revasc, revascularization; PCI, percutaneous interventions.